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GSK PRODUCTS

 SEPTRIN

Trimethoprim  sulfamethoxazole

DESCRIPTION

CLINICAL INFORMATION

Indication


Trimethoprim- sulfamethoxazole is indicated for bacterial infections of respiratory, gastro intestinal tracts

and skin, susceptible to the drug.

Dosage and Administration

Trimethoprim- sulfamethoxazole for Infusion is for administration ONLY by the intravenous route and must

be diluted before administration (See Use and Handling).

The duration of the infusion should be approximately 1 to 1.5 hours, but this needs to be balanced against the

fluid requirements of the patient.

When fluid restriction is necessary, Trimethoprim- sulfamethoxazole for Infusion may be administered at a

higher concentration, 5 ml diluted with 75 ml of glucose 5% w/v in water. The resultant solution, whilst

being clear to the naked eye, may on occasion exceed the BP limits set for particulate matter in large volume

parenterals. The solution should be infused over a period not exceeding an hour.